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IBS relief using CBD rich Sour Tsunami strain

IBS relief using CBD rich Sour Tsunami strain

CBD rich strains are great medicine for IBS and IBD. CBD makes cannabis better medicine and protects against the negative effects of THC. Check out my post ‘What’s in your cannabis’ for more information on how CBD protects you from these negative effects.

Project CBD has lots of information on high CBD strains. Below is a patient testimonial from their site discussing the benefits of CBD rich sour tsunami strain for her irritable bowel syndrome:

 

CBD rich Sour Tsunami

“I am a IBD & IBS patient that has been doing the high cbd sour tsunami hemp oil treatment now since march 4th along with my other diet and supplement regiment. Within a few days great relief to spasms, pain, bleeding and bowel incontinence had been seen. Now up to full dosage and a few weeks into treatment I have much greater relief. Down to one Bm a day from 10-20, and stools are now formed and solid. I have fully adjusted to med and now have energy during day, more stamina, and sleep unbelievably well at night. Some nights I can get 8-10 hrs straight of real REM sleep which has helped healing tremendously. The other effects worth noting are the emotional effects. The oil also keeps any stress and anxiety so common with IBD and IBS under control better than any other med out there and totally safe. The high cbd medicine makes it possible to have great relief, healing and still function during the day with no restrictive effects. I can now leave my bathroom and house and get things done and feel human again! So far I can’t say enough about the effectiveness of this treatment, I still have a few weeks to go. I will report back with new info………”
– H.J, Northern California

If you’re interested in reading more individual accounts about the healing power of cannabis, check out more testimonials on Dr. Lister Greenspoon’s site.

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Cannabis drug testing linked to spike in hard-drug use for students

Cannabis drug testing linked to spike in hard-drug use for students

Could drug testing actually be causing harm to our students?  Because cannabis metabolites remain in the urine up to 8 weeks after use, students may be choosing harder drugs that are much more difficult for these tests to detect.  There is now evidence that drug testing of students is linked to an increase in harder drug use as students seek less detectable substances.

From NORMLAnn Arbor, MI: Schools that institute student drug testing programs are likely to experience a rise in students’ consumption of so-called ‘hard’ drugs, according to observational trial data published this month in the Journal of Adolescent Health.

Researchers at the University of Michigan, Institute for Social Research analyzed the impact of student drug testing programs in some 250,000 high school and middle-school students over a 14-year period. Investigators reported that random drug testing programs of the student body, as well as programs specifically targeting student athletes, were associated with “moderately lower marijuana use,” but cautioned that drug testing programs overall were “associated with increased use of illicit drugs other than marijuana.”

An estimated 14 percent of middle school students and 28 percent of US high school students are now subject to some form of drug testing.

Urinalysis, the most common form of student drug testing, screens for the presence of inert drug metabolites (breakdown products), not the actual parent drug. Because marijuana’s primary metabolite, carboxy-THC, is fat soluble, it may be present in urine for days, weeks, or in some cases even months after past use. By contrast, most other illicit drug metabolites are water-soluble and will exit the body within a matter of hours. Authors of the study speculated that students subjected to drug screens were switching from cannabis to other illicit drugs that possessed shorter detection times.

“Random SDT (student drug testing) among the general high school student population, as well as middle and high school subgroups targeted for testing, was associated with moderately lower marijuana use; however, most forms of testing were associated with moderately higher use of other illicit drugs, particularly in high school,” authors concluded. “These findings raise the question of whether SDT is worth this apparent tradeoff.”

Commenting on the findings, the study’s lead author affirmed, “It is clear that drug testing is not providing the solution for substance-use prevention that its advocates claim.”

Previous assessments of student drug testing programs have reported that those subjected to such programs are no less likely to report consuming illicit drugs, tobacco, or alcohol than their peers.

For more information, please contact Allen St. Pierre, NORML Executive Director, at (202) 483-5500. Full text of the study, entitled “Middle and High School Drug Testing and Student Illicit Drug Use: A National Study 1998-2011,” is available from the Journal of Adolescent Health.

 

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Demystifying medical cannabis in New York State

Demystifying medical cannabis in New York State

Cannabis and addiction is a commonly discussed topic in legalization settings.  Recently experts gathered in New York to discuss this and other topics.  Enjoy this video stream of a great 2 hour forum that is relevant for medicinal cannabis, clinical, public health, and policy issues for cannabis in general.  –Jake Felice, ND

Here are the times corresponding to each speaker in the video.  In particular, pay attention to Dr. Sunil Aggarwal’s discussion about 19 minutes into the video.

00:00-02:52 Jennifer Talley, Ph.D.
02:53-07:27 John Crepsac, LCSW
07:28-18:17 Gabriel Sayegh
19:05-46:48 Sunil Aggarwal, MD, PhD
46:58-1:05:56 Julie Holland, MD
105:57-1:31:57 Andrew Tatarsky, PhD
1:31-58-2:02:39 Q&A

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Raw juiced cannabis provides green healing without smoke or sedation

Raw juiced cannabis provides green healing without smoke or sedation

The juice of raw cannabis provides unique healing benefits. Plant chemicals known as cannabinoid acids such as CBD-acids, and THC-acids break down quickly after harvest, so these compounds are not available in traditional preparations such as cooked ‘medibles’, smoking, or vaporizing.

The healing benefits of cannabinoid-acids are only present for a short period of time before the chemicals break down, so juicing needs to be done quickly after harvest. Fan leaves should make up the majority of the juice, and adding a small amount of cannabis flowers can be beneficial. Cannabis roots can also be added to the mixture as cannabis roots contain CBD, even in non-CBD producing plants!

Cannabinoid acids have amazing properties including anti-inflammatory properties, nerve protecting properties, and pain relieving properties. In raw preparations, the THC has not been heat-activated so there is not the intense sedation that is found in conventional edibles such as pot brownies. This allows for patients to take much higher doses of cannabinoids without the overly sedating effects that would otherwise be a concern. Raw cannabis shows promise for patients with neurological diseases such as MS, as well as for chronic pain suffers, cancer patients, and patients with autoimmune disease such as Crohn’s disease, ulcerative colitis, Lupus, and rheumatoid arthritis.

My patients are having fabulous success with raw juiced cannabis. The juice can be frozen to save preparation time. The freezing is typically done in ice cube trays, though it can also be blended with other juices such as apple juice and made into popsicles. Though it’s not yet being done, there is also potential to get the healing benefits of cannabinoid-acids from fresh freeze-dried preparations in capsule form. Topical application of a raw cannabis poultice is also very effective for pain from neuropathy, as well as musculoskeletal pain including arthritis pain.

Plants with high CBD content are best for juicing as they contain more CBD-acids than non-CBD producing strains.

Because of Washington state’s medical cannabis law, patients are allowed to grow up to 15 cannabis plants for their medical use. This means that patients in Seattle and throughout the state can have affordable, safe, and effective medicine for their own personal use without relying on more costly drugs with higher toxicity and side-effect profiles.

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Is cannabis a cure for cancer?

Is cannabis a cure for cancer?

We cannot yet claim at this time that cannabis can cure cancer.  Doctors, patients and scientists have however been claiming for years that tens of thousands of cancer patients have been successfully treated with cannabis.  One thing to remember with patients and cannabis is that it’s not an either/or situation. Patients can do all of their conventional therapies plus cannabis. Cannabis is so helpful for the side-effects of chemo and radiation. Patients love it and it doesn’t add to their disease burden in most cases.

Unfortunately for many cancer patients living in non-licensed states, cannabis is classified as a Schedule I federally controlled substance which means that our federal government considers it to have absolutely no medical value plus a high potential for harm.

What to do about this?  Because of its Schedule I status, research on the medical effects of cannabis has been either illegal, or very limited due to federal laws.  This study sponsored by Diego Pellicer will be one of the first to study the misinformation and myths around the question:  Can cannabis cure cancer.  With more and more research, we will finally be breaking the shackles of ignorance around the healing powers of this amazing plant.

Diego Pellicer is announcing the treatment of prostate cancer patient John Shively, age 86, with PSA = 125, using Rick Simpson Oil (RSO) cannabis treatment, and a comprehensive plan to document the process before, during and after with medical tests at various stages in the process. Once complete, they will publish and broadcast the results broadly. Upon completion, they will review and refine the methodology, and expand the study to include larger test groups, with a view to generating meaningful statistics and useful information on the effectiveness of treating cancer with RSO. The larger goal is to broadcast the objectively measured truth on this topic broadly, whatever that truth is.

Below is an excerpt from Cannabis-Med.org for readers who are interested in delving deeper into this fascinating topic:
Cannabinoids, the active components of cannabis and their derivatives, exert palliative effects in cancer patients by preventing nausea, vomiting and pain and by stimulating appetite. In addition, these compounds inhibit the growth of tumour cells in laboratory animals -mice and rats. However, at the moment there is not solid evidence to prove that cannabinoids –whether natural or synthetic- can effectively treat cancer in patients, although research is ongoing around the world.

Comprehensive FAQ sections -including scientific references- on cannabinoids and cancer can be found at the Cancer Research UK website and the National Cancer Institute of the US website. Here that information is summarized and discussed.

What is cancer?
Cancer is a broad term used for diseases in which abnormal cells divide without control and are usually able to invade other tissues, causing metastases and high rates of mortality and morbidity. Cancer is not just one disease but many diseases: more than 100 different cancers are well-typified from a histopatological point of view by the WHO and, most likely, there are hundreds if not thousands types of cancers according to molecular and genetic profiling.
Most cancers are named for the organ or type of cell in which they start. In addition, cancer types are usually grouped into the following broader categories:
– Carcinoma: cancer that begins in the skin or in tissues that line or cover internal organs.
– Sarcoma: cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue.
– Leukaemia: cancer that starts in blood-forming tissues such as the bone marrow and causes large numbers of abnormal blood cells to be produced and enter the blood.
– Lymphoma and myeloma: cancers that begin in the cells of the immune system.
– Central nervous system cancers: cancers that begin in the tissues of the brain and spinal cord.

Conclusion: Cancer is a very serious and heterogeneous disease, so fighting it therapeutically remains an extremely difficult challenge. Cannabinoids might therefore exert beneficial effects in some cancers but not in others.

Do cannabinoids inhibit cancer growth? (Laboratory research)
Virtually all the research into cannabinoids and cancer cells has been conducted so far using cancer cells grown in the lab or in animal models. Many scientific studies have reported that various cannabinoids (both natural and synthetic) exert a wide range of growth-inhibiting effects on cancer cells, including:
– Triggering cell death, through a mechanism called apoptosis.
– Stopping cells from dividing.
– Preventing new blood vessels from growing into tumours –a process termed angiogenesis.
– Reducing the chances of cancer cells to metastasize through the body, by stopping cells from moving or invading neighbouring tissue.
– Speeding up the cell’s internal ‘waste disposal machine’ –a process known as autophagy – which can lead to cell death.

Conclusion: Cannabinoids are efficacious drugs to treat at least some types of cancers in laboratory animals –mice and rats.

Do cannabinoids inhibit cancer growth? (Anecdotal evidence in humans)
As mentioned above, basically all the research investigating whether cannabinoids can treat cancer has been done in the lab. It is therefore important to be very cautious when extrapolating these results up to real live patients, who are a lot more complex than a Petri dish or a mouse. Anecdotal reports on cannabis use have been historically helpful to provide hints on the biological processes controlled by the endocannabinoid system and on the potential therapeutic benefits of cannabinoids. In the precise case of cancer there is a notable presence of videos and reports on the internet arguing that cannabis can cure cancer. These anecdotal claims may be completely or partially true in some cases, but overall remain –at least to date- weak and obscure. For example:
– We do not know whether the (supposed) effect of cannabis was due to a placebo effect.
– We do not know whether the tumour has (supposedly) stopped growing by natural/endogenous reasons -some tumours regress spontaneously/owing to the body’s anti-tumour defences.
– We do not know how many patients have taken cannabis and have not obtained any therapeutic benefit, that is, what is the (supposed) efficacy of the cannabis-based therapy.
– As most likely patients have gone through standard therapy prior to or concomitantly with cannabis use, we do not know whether the (supposed) effect of cannabis was in fact due -at least in part- to the standard therapy -perhaps enhanced by cannabis, but we have no proof.
– We do not know what are the parameters of tumour progression that have been monitored and for how long the patient has been monitored -many potentially beneficial effects of antineoplastic drugs (or of cannabis in this case) are just short-term actions, but what about long-term progression-free survival and overall survival?
– Cancer is a very heterogeneous disease, and so far none has put together a sufficient number of patients for a particular type of cancer to support that cannabinoids are efficacious drugs in that precise cancer.

Conclusion: Although it is possible –and of course desirable- that cannabis preparations have exerted some antineoplastic activity in some particular cancer patients, the current anecdotal evidence reported on this issue is pretty poor, and, unfortunately, remains far from supporting that cannabinoids are efficacious anticancer drugs for large patient populations.

Do cannabinoids inhibit cancer growth? (Clinical research)
Results have been published from only one Phase I clinical trial testing whether cannabinoids can treat cancer in patients. Nine people with advanced, recurrent glioblastoma multiforme –an aggressive brain tumour– that had previously failed standard therapy were given highly purified THC through a catheter directly into their brain. Under these conditions cannabinoid delivery was safe and could be achieved without significant unwanted effects. In addition, although no statistically-significant conclusions can be extracted from such a small cohort of patients and without a control group, the results obtained suggested that some patients responded -at least partially- to THC treatment in terms of decreased tumour growth rate, as evaluated by imaging and biomarker analyses. These findings were encouraging and substantially reinforced the interest on the potential use of cannabinoids in cancer therapies. However, they also highlighted the need for further research aimed at optimizing the use of cannabinoids in terms of patient selection, combination with other anticancer agents and use of other routes of administration.

Conclusion: There are still many unanswered questions around the potential for using cannabinoids as anticancer drugs, and it is necessary and desirable that exhaustive clinical studies are conducted to determine how cannabinoids can be used, other than for their palliative effects, to treat cancer patients.

Dr Manuel Guzman is professor at the Department of Biochemistry and Molecular Biology at Complutense University in Madrid, Spain. He coordinates the Cannabinoid Signaling Group.

 

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Cannabis blocks HIV entry into brain

Cannabis blocks HIV entry into brain

By Lynne Adkins

 

PHILADELPHIA (CBS) – A local HIV researcher has found that a substance in marijuana could keep the virus from entering the brain.

THC, the main active substance in marijuana, can block inflammation and slow down HIV”s ability to reproduce itself when it attaches to a specific protein, according to Dr. Servio Ramirez, assistant professor of pathology at the Temple University School of Medicine.

“The idea is to prevent a lot of these cells from moving into the brain during the course of infection and if you are able to suppress or somehow control hive replication in this particular immune cell, the whole hope is that less of these cells would be entering the brain through the course of infection,” says Ramirez.

He says keeping the virus out of the brain is important, because many of the drugs currently used to control HIV can’t get into the brain or are not effective once there.

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