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Dr. Jake answers your cannabis questions

Dr. Jake answers your cannabis questions

Thanks for watching CannabisMatrix.com  I’ve decided to do a series of short videos answering patient questions about cannabis.  If you find this interesting, please share with a friend.  Also, feel free to email me your questions at DrJake@DrJakeFelice.com.  As a post script, I’d like to say that I wish I would have added more information regarding the synergy between opiate medications and cannabis. Cannabis not only helps opiate medications work better, it also helps patients use less of this highly toxic class of drugs.

Below are a few more peer reviewed references supporting the facts discussed in this video:

From JAMA:  25% fewer overdose deaths from opiate pain killers in states with legal medical cannabis

Synergistic interactions between cannabinoid and opioid analgesics http://www.ncbi.nlm.nih.gov/pubmed/14706563

Synergy between THC and morphine in the arthritic rat http://www.ncbi.nlm.nih.gov/pubmed/17498686

Cannabis reduces opiate use in the treatment of non-cancer pain http://www.ncbi.nlm.nih.gov/pubmed/12782429

Synergistic and additive interactions of the cannabinoid agonist CP55,940 with mu opioid receptor and alpha2-adrenoceptor agonists in acute pain models in mice. http://www.ncbi.nlm.nih.gov/pubmed/15778704

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Photo by Derek Sparks dereksparks.com

Additionally, there is a lot of good science showing synergistic effects between the molecule CBD and THC that I did not have time to explore. Feel free to comment or email me if you have any questions regarding these synergistic effects.

Yours truly in health,

-Dr. Jake Felice, ND

CannabisMatrix.com

Seattle, WA  USA

Special thanks to Derek Sparks for the images on this post!

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Got Science? Dr. Jake’s comments to the Washington State Board of Health

Got Science? Dr. Jake’s comments to the Washington State Board of Health

The challenge to the public is that since the 1940s, medical bureaucrats and legislators have ignored the science pertaining to the use of cannabis as medicine. It is my concern that the same will be true for our Washington State Board of Health. If regulators do not understand the existing and emerging science of cannabis, they will be making poor decisions that not only do not benefit the health and well being of citizens; but could also arguably be causing harm in preventing citizens from accessing one of the least toxic forms of pain relief known to science.

Cannnabis patientSince the 1940s the federal government has commissioned expert medical panels to review scientific information about medical use of cannabis; and has done this almost every decade starting with the LaGuardia commission report in the 1940s, and continuing up to the most recent Institute of Medicine report in 1999. All of these reports repeatedly present the same conclusions based on the most up-to-date science available at the time their publication. They contain informative and straightforward information, stating the clear conclusion that scientific evidence indicates the safe and therapeutic effects of cannabis for pain.

Low toxic cannabis SanjayIf the Board of Health’s goal is to protect our citizens, the substitution of less harmful medicines in lieu of more harmful drugs, is compassionate and intelligent medicine. Cannabis is the least toxic of any pain reliever by almost any measure. It has never caused a single death, ever. Cannabis does not have to be smoked to be effective, and medical cannabis patients don’t have to get ‘high’ to experience pain relief. Over-the-counter pain relievers such as ibuprofen kill more Americans than most people are aware.

Healthy coupleAs citizens become more attuned to the benefits of cannabis as an inexpensive natural pain reliever that doesn’t have death as a side-effect, many forward thinking doctors are recognizing the amazing benefits of low-toxic cannabis for all types of pain and inflammation, including mild and moderate pain.

Cannabis is a botanical containing hundreds of pharmaceutical compounds that provide three major advantages over single molecule synthetic drugs: 1) The therapeutic effects of primary active ingredients of botanicals may be synergized with other compounds, 2) the side-effects of primary active ingredients may be mitigated by other compounds in the plant, and 3) botanicals in general, and cannabis in particular, have much lower toxicities than those of single molecule drugs.

Cannabis is a plant-based botanical medicine with extremely low toxicity. The Board of Health should understand that because of the unique nature of botanicals, the FDA actually considers botanical drugs to be in a different regulatory class from the regulatory policies applied to single molecule drugs. These federal policies are grounded in sound science, and can be referenced through the white paper published by the Department of Health and Human Services and the FDA.

Recently the Board of Health asked for public comments regarding the development of guidelines for physicians around medical cannabis. I wonder if anybody will be listening. Click here to read a copy of my letter to the board.

Thoughts or questions about this topic? I welcome your comments.

Most sincerely,

Dr. JakeDr. Jake Felice, Redmond, Washington

As a post script, I’d like to say that I wish I would have added more information to the board regarding the synergy between opiate medications and cannabis. Cannabis not only helps opiate medications work better, it also helps patients use less of this highly toxic class of drugs.

Below are a few more peer reviewed references supporting this fact:

Synergistic interactions between cannabinoid and opioid analgesics http://www.ncbi.nlm.nih.gov/pubmed/14706563

Synergy btw THC and morphine in the arthritic rat http://www.ncbi.nlm.nih.gov/pubmed/17498686

Cannabis reduces opiate use in the treatment of non-cancer pain http://www.ncbi.nlm.nih.gov/pubmed/12782429

Synergistic and additive interactions of the cannabinoid agonist CP55,940 with mu opioid receptor and alpha2-adrenoceptor agonists in acute pain models in mice. http://www.ncbi.nlm.nih.gov/pubmed/15778704

Additionally, there is a lot of good science showing synergistic effects between the molecule CBD and THC that I did not have time to explore in this letter. Feel free to comment or email me if you have any questions regarding these synergistic effects.

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Medical cannabis for kids???

Medical cannabis for kids???

Do you think medical cannabis is just for stoners?  Take a look at this little girl who uses large amounts of medical cannabis to treat her epilepsy.  You might just find yourself shedding a tear.

Cannabis offers effective, low toxic options for patients with seizure disorders and can even be helpful for petiatric patients.  Newer strains of high-CBD, low-THC cannabis such as Charlotte’s Web provide safe, effective seizure relief that can really work.  -Dr. Jake Felice

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Fear Factor host vs Ann Coulter on cannabis – it’s not pretty…

Fear Factor host vs Ann Coulter on cannabis – it’s not pretty…

In the video below, Ann Coulter is destroyed by Fear Factor’s Joe Rogan, and it’s not pretty.  Just one fact correction – About 2 minutes into the video, Joe Rogan says that CBD’s must be extracted, as in they must be extracted by laboratory techniques.  Luckily, this is not true.  The truth is that you don’t even need a lab to get high quality CBD medicine.  CBD’s are present in whole plant cannabis including many cannabis strains, as well as hemp based products.

That’s right, HEMP!  The CBD in hemp can be extracted directly into olive or coconut oils for medical use utilizing simple kitchen tools and a heat source such as a crock pot.  And this is legal in all 50 states.  If it sounds like too much trouble to do yourself, hemp creams and oils are available for sale in all 50 states and can be used by patients topically for pain relief.  High CBD hemp oil can even add benefit to topical cannabis creams as many topical cannabis lotions do not have CBD’s in them.  Botanically speaking, hemp is cannabis too.  Ooooh yeah…!  -Dr. Jake

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How medical cannabis affects the brain and all vital organs

How medical cannabis affects the brain and all vital organs

Scientific research and real facts about the healing benefits of medical cannabis and cannabinoids including CBD.  –Dr. Jake Felice

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Topical cannabis is effective for skin conditions

Topical cannabis is effective for skin conditions

I can say that I have personally seen amazing results with patients using topical cannabis for skin conditions such as eczema, psoriasis, sunburn and poison ivy rashes and more.  Here is some new scientific data supporting what we already see is true clinically, namely that cannabis topicals can provide low toxic relief to patients with both chronic and acute skin conditions.  -Dr. Jake Felice

From TheJointBlog

A new study, recently published online in the British Journal of Pharmacology, details how cannabinoids can play a role in the treatment of skin diseases.

Researchers looked at the impact of phytocannabinoids (plant-derived cannabinoids, rather than synthetic counterparts) on epigenetic regulation of skin differentiation genes.

The study found that both cannabidiol (CBD) and cannabigerol (CBG), “significantly reduced the expression of all genes tested via increased DNA methylation for keratin 10 gene”.

The CBD was found to reduce keratin 10 mRNA through stimulating type-1 cannabinoid (CB1) receptors, while the CBG was found to act through a secondary method that did not engage the CB1 or CB2 receptors of keratinocytes (HaCaT cells). It was also revealed that cannabidiol increased global DNA methylation levels.

The study concludes that cannabis could act as a primary treatment for epidermal ailments:

“These findings identify the phytocannabinoids cannabidiol and cannabigerol as transcriptional repressors that can control cell proliferation and differentiation, suggesting (especially for cannabidiol) a possible exploitation as lead compounds to be used in the development of novel therapeutics for skin diseases.”

This report was conducted by researchers at the University of Teramo, the Campus Bio-Medico University and the Santa Lucia Foundation, all located in Italy.

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